Anime - Folder to store my exceptionally large amount of anime. Over 10 gigs in one folder.
My Documents - For easy-accessing. Still, I use the link in the 'start' panel, so I'd say this is pretty useless.
Miscellaneous - This folder is pretty pathetic, actually. I have 300 megs of just random stuff ranging from fonts to programs. I usually just throw all junk that I have on my desktop into this folder. I'm too scared to delete any of it because I use so many programs. And I'm also too lazy.
AOL Instant Messenger - Self-explanatory.
MSN Messenger - Self-explanatory.
Verizon Control Pad - Stupid thing to start up the internet. I never use it, but it's locked on my desktop. How troublesome.
Full Metal Alchemist - 20 Megs worth of pictures.
Naruto - 40 Megs worth of pictures.
Hikaru no Go - 2 Megs worth of pictures. Just started finding Hikago pics.
My Received Files - All of my downloads go into this folder, so I keep it here for easy accessing.
Manga - Folder for my Gig-worth of manga. God, I'm such a loser.
Video Games - I have a shitload of Final Fantasy, Naruto, Hikaru no Go, and Yu-Gi-Oh! games (yes, they're old =P) on here. Oh, and I also have a rare Full Metal Alchemist game that is pretteh fun. These are only for SNES and NES.
Emulators - It's not that hard to keep all of my emulators in here. They clog up my desktop and come with a lot of those stupid "Read Me"'s. I just keep all of that shit in here.
Spybot - I have so much spyware it's not even funny. I have to run a check every day or two.
iTunes - My favorite media player. If I'm bored with my playlist, I just switch onto the Radio mode. So many stations to choose from.
Sakura Blossoms - Quick link to my fic. I should be updating it right now, actually. I'm gonna write the next chapter tonight.
Manga Viewer - The best manga viewing program out there. Just put in the file, and click a button for the next page to load. It's a lot better than constantly clicking the pages that you want to view out of the zipped folder. -_-
Mike's Pictures - Sometimes I hunt for random icons and avatars. When I do, I drag them to my desktop and drag those into this folder.
Jasc Paint Shop Pro 8 - I was using Photoshop for a while, but figured that my work was better on PSP8. Has some cool features, and I've been using it for so long that switching is too hard for me.
Kazaa Lite K++ - I think this is the best Kazaa version. I only really use this for music downloads, if I can't find HTTP or FTP links.